10 replies to this topic

[topperf]

http://www.dailymail...-use-hands.html

Now! thank you.

[topperf]

Oh.. You have.. :-) I just got really exited.

[SnoFl]

Thanks for sharing.
Glad there is potential healing for future cervical SCI's.

[edlee]

I really hope that this turns out to be valuable line of research,, and not merely a valuable line for research grants.

I've heard similar stories so many times,,,, but still I hope for the best.
ed

[Illinois Boy]

Maybe I'll hang on to my 57' Strat awhile longer........
Would love to play her again.....

Jim

[topperf]

Illinois Boy, on Aug 15 2009, 07:05 PM, said:

Maybe I'll hang on to my 57' Strat awhile longer........
Would love to play her again.....

Jim

Precisely - I've got one or two I thought about getting rid of not so long ago - (not that pristine, so few are) - but I'll hang on to them a little longer.

[Jax]

Seriously? How many people actually think that the Brits are the first to try chondroitinase? They can't honestly say that the use of chondroitinase is a new thing. It was done in Russia on humans a decade ago (in conjunction with adult autologous repair cell injection), and on humans in Lisbon, Portugal back in '01-'03 (in conjunction with olfactory mucosa autograft)!

Hardly anybody cared when China, Russia, or Portugal did it in humans, but now that the Brits do it in rats, it's "new" and great?! WTF is wrong with this world?! It doesn't have to be done in the US or UK to be good and viable!! Just because the US and UK had their heads run up their arses for a decade doesn't make them somehow ahead of the game now!

Oh, well. It's a lost cause trying to make people see what they don't want to see.

[GLENDA]

Jax, on Aug 18 2009, 05:05 PM, said:

Seriously? How many people actually think that the Brits are the first to try chondroitinase? They can't honestly say that the use of chondroitinase is a new thing. It was done in Russia on humans a decade ago (in conjunction with adult autologous repair cell injection), and on humans in Lisbon, Portugal back in '01-'03 (in conjunction with olfactory mucosa autograft)!

Hardly anybody cared when China, Russia, or Portugal did it in humans, but now that the Brits do it in rats, it's "new" and great?! WTF is wrong with this world?! It doesn't have to be done in the US or UK to be good and viable!! Just because the US and UK had their heads run up their arses for a decade doesn't make them somehow ahead of the game now!

Oh, well. It's a lost cause trying to make people see what they don't want to see.

Do you know what the outcome of the use of chondroitinase was in the other countries.....
I live in Houston Texas. Son is c4 c5 recent injury. I am contantly researching. You sure are up on your research! What else do you know?

[Jax]

GLENDA, on Aug 18 2009, 07:06 PM, said:

Jax, on Aug 18 2009, 05:05 PM, said:

Seriously? How many people actually think that the Brits are the first to try chondroitinase? They can't honestly say that the use of chondroitinase is a new thing. It was done in Russia on humans a decade ago (in conjunction with adult autologous repair cell injection), and on humans in Lisbon, Portugal back in '01-'03 (in conjunction with olfactory mucosa autograft)!

Hardly anybody cared when China, Russia, or Portugal did it in humans, but now that the Brits do it in rats, it's "new" and great?! WTF is wrong with this world?! It doesn't have to be done in the US or UK to be good and viable!! Just because the US and UK had their heads run up their arses for a decade doesn't make them somehow ahead of the game now!

Oh, well. It's a lost cause trying to make people see what they don't want to see.

Do you know what the outcome of the use of chondroitinase was in the other countries.....
I live in Houston Texas. Son is c4 c5 recent injury. I am contantly researching. You sure are up on your research! What else do you know?

It's not the chondroitinase alone that makes for the best results. Even Mark Bacon (member of the British SCI research group Spinal Research) says in his interview regarding chondroitinase that the protein will be most effective when used in conjunction with other procedures (even in rats). The procedures that chondroitinase has been used in most (so far) have been the 2 listed above--autologous repair cell injections, or olfactory mucosa autografts (not quite the same as the olfactory ensheathing cell procedure). The chondroitinase is just what they say it is--a part of what's needed for achieving the maximum results in repairing the spinal cord.

It's also a bit different repairing SCI in humans than rats. I know that they used the part of the rat C-spine that is the closest to the C-spine of humans, but it's still not the same. The human spine is a larger piece of "cable" (if you will) than that of the rats. Just using a higher dose of chondroitinase for humans won't do the whole splice job alone. The area of the human spinal cord is larger, therefor, many of the lesion sites are larger, and therefor the area of the scar tissue buildup is greater. That means that the time it would take for the chondroitinase to have the same affect on the human SCI would be longer. This means that for maximum repair potential to be achieved, there has to be introduction of some new neurons or repair cells, in order for the gap to fill more quickly and solidly. Sort of like soldering wires together versus using black tape.

Almost forgot this part-They're also doing these tests on recently injured rats. Post injury time among humans showed no significance in Dr. Lima's procedure, but the difference in results between recently injured rats and long-ago-injured humans is yet to fully be determined.

Check out the Repair Stem Cell Institute website. I get their newsletter via email. Also, check out this pdf file. It's the clinical study report from Dr. Lima and co-researchers in Lisbon. What's been done with the cells of both types is simply the addition of chondroitinase to the cells to aid in their regrowth and culturing. The cells are then injected/implanted into the spinal cord. I have met 1 quad and 1 para who've been to Russia. Both have regained at least some bladder and bowel function along with some sensation. The quad has regained some hand function (from what I surmise and have heard/read here, that alone is enough for most to warrant the procedure should it be affordable.). Also, you might want to check out the Stemcellblogger website for some other interesting information. I've gotten a bit behind recently, so I'm sure there is even more on that site than I remember.

Edited by Jax, 19 August 2009 - 05:25 AM.

[Illinois Boy]

Thamks for drowning my hopes, Jax.....

Time to sell it all.......

Jim

[Jax]

Sorry man. I know how much that strat means.

If regaining those little bits is worth that much to you, then yeah, go for it. It is to me. Being able to feel my d!ck again would be awesome! And $30,000 doesn't seem all that unreasonable a price for it for me, even if it takes several years to fully work. Hell, I'd sell my legs on the black market for that feeling.

For some, however, there are the unreasonable expectations of instant results like some "magic pill" that will make them all better. That's just not the way the body works, not even with something as simple as a small scratch. There is always a time factor, and the more complex the injury or injured system, the longer the repair will take.