[dangerousdave]

Hi everybody .. time for a question / comment

Just ordered some D-Mannose from Sweet Cures
On their site is a report that basicly states that the acid in CJ supports and feeds E-Coli , leading to repeat infections
As every morning for the last 9 years I've started my day with a glass of Cranberry Juice
This year though I have been plagued with UTI's
Any thoughts circling out there in cyber space as this is the first Ive heard of such reports

E.coli loves Cranberry!
Proof!
That statement probably surprises you, but E.coli is an acid adaptive bacterium, and is capable of synthesising its nutritional requirements from the surrounding acids in its environment. Since cranberry creates acidic urine conditions, [Proof!] (cranberry juice produces hippuric acid in the urine) when you drink cranberry or eat cranberry tablets, you are giving E.coli a suitable environment in which to multiply.

http://www.sweet-cur...i-cranberry.htm

[Apparelyzed]

Don't forget that they want you to buy their product, so they will take anything they can to discredit any other products which do the same job.

Cranberry Juice doesn't stop E-Coli from producing, but instead works by inhibiting the adhesion of type I and P-fimbriated uropathogens (e.g. uropathogenic E. coli) to the uroepithelium, thus impairing colonization and subsequent infection.

Cranberry is a preventative measure, not a cure for UTI's.

Simon

Source: http://www.ncbi.nlm....pubmed/19441868

[edlee]

Reading the end of the above linked document, I found most enlightening.

Quote

). In general, the preventive efficacy of cranberry has been variable and modest at best. Meta-analyses have established that recurrence rates over 1 year are reduced approximately 35% in young to middle-aged women. The efficacy of cranberry in other groups (i.e. elderly, paediatric patients, those with neurogenic bladder, those with chronic indwelling urinary catheters) is questionable. Withdrawal rates have been quite high (up to 55%), suggesting that these products may not be acceptable over long periods. Adverse events include gastrointestinal intolerance, weight gain (due to the excessive calorie load) and drug-cranberry interactions (due to the inhibitory effect of flavonoids on cytochrome P450-mediated drug metabolism). The findings of the Cochrane Collaboration support the potential use of cranberry products in the prophylaxis of recurrent UTIs in young and middle-aged women. However, in light of the heterogeneity of clinical study designs and the lack of consensus regarding the dosage regimen and formulation to use, cranberry products cannot be recommended for the prophylaxis of recurrent UTIs at this time.

My underlining and highlighting

I stopped using cranberry about a year ago, when my new urologist told be it wasn't a "viable tool". Don't you love it when they talk technical?? He told me that a more valuable regimen would be Vit C ,, but he put me on a low dose of Microbid as well. I've had less recurences,, but not a lot less.. in fact, I'm on antibiotics as I type this, for my latest round.
ed

[dangerousdave]

Hi BOSS

Of cource it is correct to think twice about info supplied on company sites
I didn't even know about D-Manosse until I joined this site
Alas we all use some sort of bladder management system
It would seem from the postings on our site that repeat infections are becoming a big issue
From 2000 infections were singular events with long periods of trouble free time for me
This year has been one of repeat infections that I have now found respond to daily use of
D-Mannose. As Cranberry Juice is also a daily drink since befor 2000, I have no wish to give it up and sart taking another tablet

Perhaps a new question
How long from the start of bladder management until the onset of repeat infections ?
For me 8yrs

[Apparelyzed]

Quote

Perhaps a new question
How long from the start of bladder management until the onset of repeat infections ?
For me 8yrs

I guess the answer to that question has so many variables, that there is no easy answer, as it depends on management technique, medication, gender, hygene etc.

I last had a bladder infection in 1992, all I do is keep drinking plenty of fluids, and maintain good hygene, but there will be others who do this, and still get infections.

Simon.

[dangerousdave]

I guess the answer to that question has so many variables, that there is no easy answer, as it depends on management technique, medication, gender, hygene etc.

Very true Boss
If it's a medical paper I'd agree there would be 100's of questions
The 2 main facts though would still be time and a juice drink
From the moment we start a system we are told to include a juice drink
So ignoring the variables .. the basic question stands

[Apparelyzed]

For some, D-Mannose will work, others Cranberry will work, some just have a genetic pre-disposition to infections whilst other have a higher immune system to such infections.

I guess unless you try these different methods, then you will never know what works, and what doesn't.

All part of the baggage which unfortunately comes with SCI.

Simon

[edlee]

Quote

All part of the baggage which unfortunately comes with SCI.

And what a lot of baggage it is, too.
ed

[StillFingers]

As has been said, damn UTI baggage, three SCI decades past and what I've found is a high acid diet, drinks in particular, if consumed in excess or for extended periods of time, do tend to promote more UTI bacterial growth. Cranberry juice does seem to help but is high in acid and often high in sugar/calories.

I have for the last ten years used both cranberry juice lite, low sugar, and some rather high potency cranberry extract capsules. I take both daily, 3ounces of cranberry juice in 8ounces of water, 2 capsules per day with 8ounces of water per capsule; I split these up between my day, morning, mid day then early evening; see link below for the cranberry capsules I use...

I still get a UTI on occasion, but very rarely...I drink lots of water per day tho, 2 liters or more.

Regards,

Jerry

Access To Recreation
http://www.accesstr.com/AMAZING/itemdesc.a...amp;eq=&Tp=

This post has been edited by StillFingers: 16 November 2009 - 11:10 PM

[jules]

I had to stop having my cranberry juice (which always worked very well for me) when I was put on Warfarin for my pulmomary embolism, the only plus point of my bleed last week and having to go on to heparin (fragmin) injections is that I can now have cranberry juice again because the fragmin is not affected by cranberry like Warfarin is