MAGANGA, on Jan 30 2008, 06:22 PM, said:
Thanks K, I really really appreciate for your help and your time, that why I like this forum
Hi MAGANGA,
You may find the following of use too:
Research displayed in Neurochemical Research Journal is available to see in Ingentaconnect.com. It is regarding research done in Rats whereby Methylprednisolone and Hyperbaric O2 therapy was used after the Rats were SC injured.
Research details.
Another Abstract regarding HBO can be viewed
HERE
Another 'take' on the HBO therapies can be viewed @ sciencedaily.com
Click Here its more historical as was conducted in 98.
"James (Dr P James, Uni Dundee) cautioned that hyperbaric oxygen therapy, as the high-pressure procedure is called,
is useful only in cases where the spinal cord is bruised, but not in cases where it is physically severed."
Another find, is a site which is dedicated to SCI:
http://www.sci-therapies.info/HBO.htm which states it is a site which is looking at "HUMAN SPINAL CORD INJURY:
NEW & EMERGING THERAPIES"
QUOTED TEXT FOLLOWS regarding site
Icelandic Health Authorities and the World Health Organization (WHO) with the support of the Council of Europe have launched an international effort to accumulate information on various therapies and procedures that have the potential to restore function in people who have sustained a spinal cord injury (SCI).
The project is built on a belief that if we can open-mindedly integrate the divergent pieces of the puzzle that exist throughout the world - whether they originate in the US, China, Russia etc., whether they reflect the perspectives of Western or Eastern medicine, or whether they reflect the contributions of large medical centers or small clinics - restoration of function is a real-world possibility now and not just some distant pie-in-the-sky possibility.
The overall goal of this database is to make information on diverse therapies more readily available to people with SCI, their family, friends, and caregivers.
With regards to Hyperbaric O2 therapies, the site quoted above has some resources which refer to studies and their outcomes ( in their interpretation):
QUOTED TEXT FOLLOWS:
HBO & Acute Spinal Cord Injury
Dr. John Yeo (Australia)
Dr. Richard Jones (Australia)
Dr. Francis Gamache (USA)
Dr. M.P. Elinskii (Russia)
Dr. S. Asamato (Japan)
HBO & Chronic Spinal Cord Injury
HBO & Stem-Cell Mobilization
Hyperbaric oxygen therapy (HBO) is most commonly used to treat decompression sickness or the bends in divers who undergo rapid decompression. Patients are placed in chambers pressurized at 2-3 atmospheres containing up to 100% oxygen (compared to 21% in the air we breathe). This pressure allows the bubbles resulting from rapid decompression to be reabsorbed.
Evidence from animal and human studies suggests that HBO is beneficial for treating a variety of neurological disorders in which blood-flow-related oxygenation may be compromised (i.e., ischemia), including stroke, head injury, and acute and perhaps chronic SCI. The therapeutic premise is that HBO will force oxygen into oxygen-deprived CNS tissue resulting from injury. Dr. Wise Young (NJ, USA) has reviewed HBO therapy, including potential SCI applications (http://carecure.rutg...es/HBOT2001.htm). HBO has also been used to accelerate healing in SCI-associated pressure sores.
HBO & Acute Spinal Cord Injury
1) In 1978, Dr. John Yeo and colleagues (Australia) reported on the HBO treatment of 10 patients with acute SCI (Med J Aust 2(12), 1978). Eight and two patients had quadriplegia and paraplegia, respectively, and three had complete injuries. HBO treatment, consisting of two 90-minute, 2.5-atmospheres sessions, commenced within 14 hours of injury. Results suggested that recovery of motor power in five patients was more rapid and greater than would be expected from routine care.
In 1984, Yeo indicated that he had cumulatively treated 45 acutely injured patients with HBO (Central Nervous System Trauma 1(2), 1984), of whom results were reported for 27 with upper motor neuron lesions. Of the 27, 78% and 22% had cervical and thoracic injuries, respectively, and average age was 32. Patients received up to three 90-minute, 2.5-atmospheric pressurizations starting 5-14 hours after injury and were compared to 63 conventionally treated patients using the Frankel assessment scale, the predecessor to today’s commonly used ASIA scale.
Although 15 of the 27 patients had useful functional recovery, overall no statistical difference was demonstrated between treated and control patients. Yeo suggested, however, “the trend indicates that the patient with an incomplete spinal cord injury may experience additional functional recovery if treated with HBO… within hours of injury.”
2) In 1978, Dr. Richard Jones et al (Sydney, Australia) reported the results of treating nine patients with HBO within 12 hours of injury (Med J Aust 2(12), 1978). Each patient had two 120-minute, 2.5-atmospheric sessions (equivalent to a depth of 45-feet sea water) separated by an hour of normal pressure breathing. Of the treated patients, several had functional or neurological improvement.
3) In 1980, Dr. Francis Gamache and colleagues (NY, USA) presented the preliminary findings of treating 25 patients with HBO starting about 7.5 hours after injury (Surgical Neurology. 15(2), 1981). Twenty-three were male; 19 and three had cervical and thoracic injuries, respectively; and age averaged 24. Patients were treated for 90-120 minutes at 2.0-2.5 atmospheric pressure at intervals ranging initially from every two hours to twice daily. Treatment was discontinued when improvement reached a plateau. Patients were periodically evaluated for at least six months. The investigators concluded that HBO accelerated recovery, though final outcomes were comparable to those patients receiving conventional care.
4) Dr. M.P. Elinskii and colleagues (Russia) concluded that 2.8-atmospheric-pressure HBO therapy reduced neurological symptoms in patients with various spinal cord lesions (Zh Neropatol Psikhiatry Im S S Korsakova 84(5), 1984).
5) Dr. S. Asamato et al (Tokyo, Japan) retrospectively compared 34 patients with cervical, hyperextension injuries who had and had not been treated with HBO therapy (Spinal Cord, 38(9), 2000). In HBO-treated patients, improvement ranged from 100% to 27.3% with a mean of 75.2%, whereby in the non-HBO treated group, these values were 100%, 25%, and 65.1%, respectively. The investigators concluded that the data “indicated effectiveness in acute traumatic cervical injury.”
HBO & Chronic Spinal Cord Injury
Various anecdotal reports indicate potential benefits may accrue for individuals with chronic SCI. For example, an Australian HBO program has reported functional improvement in several patients with chronic SCI (www.spinalrehab.com.au/disorders/SpinalCordInjury.htm). In one case, a 39-year old male had sustained C6-7 injury from an auto accident and further developed a C6-T1 syringomyelia cyst. Several years after injury, he commenced daily HBO therapy and reported as a result the return of sensation in legs down to his toes, stomach, and back, as well as the return of knee reflexes.
The second case involved a 20-year-old female who had sustained a C5-6 injury from an auto accident. Before commencing HBO therapy, her improvement had been minimal. In addition to HBO treatment, she also received “assertive” physical therapy and electro-acupuncture, both of which have been shown to promote functional recovery. In a diary, she documented the incremental improvements she accrued over the course of 70 HBO pressurizations, which cumulatively were considerable, including improved bowel-and-bladder and respiratory function, circulation, pressure-sore healing, and sensation and motor control in extremities.
HBO & Stem-Cell Mobilization
Given the many potential stem-cell therapies emerging for SCI, it is interesting to note that Dr. Stephen Thom and colleagues (Pennsylvania, USA) that HBO therapy stimulates the bone-marrow production of stem cells through a mechanism dependent on nitric oxide, a chemical that plays a key role in the spinal cord injury process (Am J Physiol Heart & Circ Physiol, November 18, 2005). Specifically, the number of stem cells doubled in the circulation of humans after a single two-hour, two-atmosphere HBO session, and after 20 treatments, increased eight-fold.
I hope that these help,
take care,
K
Edited by kewlcatkez, 30 January 2008 - 06:49 PM.
0
One of my friend told me about Hyperbaric-Oxygen Therapy , what it is please help me , I tried to search through the net but I am getting difficult to get correct information, Also I will be appreciate if some one know any information about National Hyperbaric Hospital 
Help me
Top