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Spinal Cord Injury Cure & Research News

Welcome to SCI News, the corner of the internet which collates news relating to Spinal Cord Injuries and Research. All the articles below are on their respective publishers websites to preserve copyright, A new window will be launched when you click any of the links below. If you find an article below which has expired, please let us know by using the email form on our About page.

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Date
Subject
Extract
Dec 03 2004 Harvesting Stem Cells from Fat Tissue "Researchers are actually finding those repairing cells, called stem cells, in human fat tissue taken from liposuctions."
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Nov 12 2004 Damaged spinal cord grows back "University of Melbourne's Professor Mary Galea and team found that removing the molecule known as EphA4 resulted in significant regrowth of the spinal nerves.
Mice without EphA4 regained their full stride length within three weeks of injury and within a month had regained ankle and toe movement."
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Nov 11 2004 Spinal Cord Nerve Regeneration Occurs in Absence of Nogo Receptor "Mice engineered without the Nogo-66 Receptor (NgR) grew new nerve fibers after spinal cord injury, pointing to this receptor as a target for development of a drug to promote fiber recovery, according to a Yale study published today in Neuron."
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Oct 27 2004 Several new techniques show promise for spinal cord repair "Novel methods for transplanting cells into areas damaged by spinal cord injury and experimental drug treatments show promise for aiding those suffering from injury to their spinal cord. "
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Oct 26 2004 Nerve Navigation Findings Prompt New Direction for Spinal Cord Research "A piece of the puzzle of how nerves find their way across the midline of the brain and spinal cord in a developing embryo has been found by Medical College of Georgia researchers. "
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Oct 11 2004 Three-Step Paralysis Treatment "Neuroscientist Mary Bartlett Bunge is working at the Miami Project to Cure Paralysis at the University of Miami. She has helped develop a "triple play," combining three treatments believed to help paralysis when used individually."
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Oct 06 2004 Spinal Cord Repair Trials Given Go-Ahead "Human trials of a technique with the potential to repair spinal cord injuries are set to start within three years, experts said today. The work, which could help thousands of disabled people regain movement, will be carried out at University College London’s new Spinal Repair Unit. The plans were outlined today as UCL launched a £300 million fundraising campaign to boost work across the university".Read Article >>>>
Sept 10 2004 Spinal cord injury specialist says 60 percent of his patients are obese "Gater’s research team has begun several new studies to look at how people with spinal cord injury burn calories, why their energy expenditure is different and how to deal with the disproportionate rate of obesity among these patients."
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Sept 09 2004 Extreme Stretch-growth Of Axons: Pushing Neurons' Physiological Limits Provides Researchers With New Ways To Repair Nerve Damage. "Sometimes it is the extremes that point the way forward. Researchers at the University of Pennsylvania School of Medicine have induced nerve fibers – or axons – to grow at rates and lengths far exceeding what has been previously observed. To mimic extreme examples in nature and learn more about neuronal physiology, they have mechanically stretched axons at rates of eight millimeters per day, reaching lengths of up to ten centimeters without breaking."
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August 12 2004 Mouse Spinal Cord Compression Injury Ameliorated by Aeolus Catalytic Antioxidant "RESEARCH TRIANGLE PARK, N.C., Aeolus Pharmaceuticals, Inc. announced that its catalytic antioxidant, AEOL 10150, demonstrated sustained benefit in a mouse model of spinal cord compression injury."
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July 28 2004 Scientists Finger Surprise Culprit in Spinal Cord Injury "ATP, the vital energy source that keeps our body’s cells alive, runs amok at the site of a spinal cord injury, pouring into the area around the wound and killing the cells that normally allow us to move, scientists report"
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July 13 2004 Antibody Block Helps Regenerate Spinal Cord "An antibody treatment that neutralizes a nerve growth inhibitor has repaired damaged spinal cords in rats and could do the same in humans."
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July 13 2004 Nerve Cells Successfully Regenerated
Following Spinal Cord Injury
"Using a combination of therapies and cell grafts, a team of University of California, San Diego (UCSD) School of Medicine researchers has promoted significant regeneration of nerve cells in rats with spinal cord injury."
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July 07 2004 Mitochondria in spinal cords is ALS target according to UCSD medical researchers "The selective killing of spinal cord neurons in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, occurs when tiny cellular components called mitochondria actively recruit a mutant disease-causing protein into specific neuron cells, according to new research by University of California, San Diego (UCSD) School of Medicine investigators."
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July 01 2004 Research describes how nerve growth factor stimulates a sequence of proteins that promote nerve growth

"Scientists at the University of North Carolina at Chapel Hill have discovered key steps involved in regulating nerve growth and regeneration that may have implications for spinal cord research."
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June 8 2004 Chinese doctor claims success in easing paralysis "The OEG cells, found above the bridge of the nose at the base of the brain, are the only nerve cells in the body that regenerate throughout life. Fetal OEG cells are more potent than those taken from adults. Huang and his team grow more fetal OEG cells in a culture, then transplant about a million of them slightly above and below the injured part of the spine. Two or three days after the operation, many paralyzed patients regain some sensation and movement."
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May 23 2004 Combination therapy dramatically improves function after spinal cord injury in rats "A combination therapy using transplanted cells plus two experimental drugs significantly improves function in paralyzed rats, a new study shows. The results suggest that a similar therapy may be useful in humans with spinal cord injury. "
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April 28 2004 Developing a new way to bypass spinal cord injuries. "Researchers are developing a new way to bypass spinal cord injuries to reconnect nerve communication to the brain. This ScienCentral report investigates whether the technique can restore movement in people with paralysis."
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April 22 2004 New Study Finds Spinal Cord Stimulation Pays for Itself in 2.5 Years "Beyond the documented relief provided to victims of chronic pain, a new study of spinal cord stimulation (SCS) suggests these therapies also offer economic benefits by paying for themselves in less than 2.5 years, according to a report in the current issue of the Journal of Pain and Symptom Management."
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Mar 8 2004 Reduced scarring helps nerves grow through spinal injuries "Infusing a naturally occurring anti-scarring agent called decorin into the damaged spinal cords of rats suppresses key molecules that block nerve regeneration after spinal cord injury, said Baylor College of Medicine (BCM) researchers in a study published today in the European Journal of Neuroscience."
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Feb 25 2004 Antibiotic Provides Promise In Treatment Of Spinal Cord Injuries "Researchers at Brigham and Women's Hospital (BWH) and Children's Hospital Boston (CHB) have found that a commonly prescribed antibiotic could be used to help prevent paralysis and other long-term functional deficits associated with a partial spinal cord injury (SCI)."
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Feb 21 2004 Secondary complications and restoration of function in Spinal Cord Injury " Identical twins studied to determine impact of SCI on energy expenditure and lean muscle mass
Investigators measured energy expenditure and fat-free mass, as well as the relationships between these parameters, in persons with spinal cord injury (SCI)."
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Feb 15 2004 Neurologists create a font of human nerve cells " Scientists have created an unlimited supply of a type of nerve cell found in the spinal cord – a self-renewing cell line that offers a limitless supply of human nerve cells in the laboratory. Such a supply has long been one goal of neurologists anxious to replace dead or dying cells with healthy ones in a host of neurological diseases."
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Jan 24 2004 When one leg walks, the other listens

"They said patients whose spinal cords were severed were nonetheless able to move their legs with the help of therapists."
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Jan 23 2004 Scientists Grow Neurons Using Nanostructures "EVANSTON, Ill. --- Scientists at Northwestern University have designed synthetic molecules that promote neuron growth, a promising development that could lead to the reversal of paralysis due to spinal cord injury."
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Jan 20 2004 Nerves, Heal Thyselves - Scientists Reveal Key Part of Nerve Regeneration "A new study has now uncovered a key process leading to the regeneration of peripheral nerves. Knowing how neurons in the peripheral nervous system regenerate could provide insights into fixing neurons in the central nervous system where damage is irreversible."
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Jan 5 2004 Exercise therapy gives student hope "The therapy stems from the premise that encouraging individuals to use a partially paralyzed limb is effective because forced movements might stimulate damaged nerve cells to relearn their jobs"
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Dec 12 2003 Chemical gradient steers nerve growth in spinal cord "A research team at the University of Chicago has discovered a crucial signaling pathway that controls the growth of nascent nerves within the spinal cord, guiding them toward the brain during development. The study, published in the Dec. 12, 2003, issue of the journal Science, solves a long-standing scientific mystery. It may also help restore function to people with paralyzing spinal cord injuries."
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Dec 09 2003 ProNeuron to test spinal cord treatment in U.S. "NEW YORK (Reuters) - ProNeuron Biotechnologies Inc. on Monday said it was beginning U.S. clinical trials of an ambitious new drug aimed at improving the condition of patients who would otherwise remain paralyzed throughout their lives."
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Dec 02 2003 Mayo scientists develop implant that could repair spinal cords "Researchers at the clinic have coaxed severed spinal nerves in rats to grow by building a bridge across the gap in the cord and seeding it with special molecules. "
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Nov 30 3003 Monkey test offers hope to paralysed "Scientists in Switzerland have successfully regenerated nerve fibres in the damaged spinal cords of monkeys. The result paves the way for human trials for spinal cord regeneration, which could begin next year."
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Nov 23 2003 State House sends mixed message on spine cord injuries "On Wednesday, members of the Legislature's Health Care Committee endorsed a bill that calls for adding a $50 surcharge to speeding tickets and other moving violations and using the proceeds to create a Spinal Cord Injury Trust Fund.."
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Nov 19 2003 MEPs back research on stem cells "Members of the European Parliament have voted to allow EU money to be used to fund research on embryonic stem cells. They backed the European Commission proposals to lift the current ban imposed in some EU states where using human embryos in research is banned."
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Nov 18 2003 New study may explain spinal cord pain. "A new study by Yale researchers has found a possible explanation for chronic pain in patients with spinal cord injuries."
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Nov 17 2003 Feeling restored after paralysis. "Scientists say they have successfully restored feeling to patients paralysed for at least two years. A team from the University of San Paulo in Brazil said 12 out of 30 spinal cord patients responded to electrical stimulation of their paralysed limbs. The researchers harvested stem cells from the patients' blood, and reintroduced them into the artery supplying the area which was damaged."
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Nov 13 2003 Blocking immune response to spinal cord injury can improve chances for recovery. "People who suffer spinal cord injuries may have a greater chance of recovery if treated with drugs that block the body’s own immune response to the initial trauma, researchers from the Reeve-Irvine Research Center at UC Irvine have found."
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Nov 10 2003 Exercise may speed spinal cord repair. "Exercise speeds the recovery of rats with spinal cord injuries, a new study suggests. Regular runs prompt the release of chemicals that help damaged nerve cells communicate. The finding adds to evidence that workouts may hasten rehabilitation in humans with spinal cord injuries."
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Oct 31 2003 Surgery Helps Cancer Patients With Spinal-Cord Compressions to Remain Mobile. "For patients with spinal-cord compressions caused by cancer metastasis, radical direct decompressive surgery plus postoperative radiotherapy is much more effective than radiation alone, a new study finds."
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July 28 2003 Chemical nerve signal discovered "Scientists have found a chemical which can influences the direction of nerve cell growth - and say it could help repair damaged spinal cords. One of the reasons that severe spinal cord injury causes permanent damage is that the nerve cells involved do not regrow in the same way as normal cells."
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